Sounds like I need to play The Last of Us. I have Brothers, but I never got around to finishing it.
A game that made me cry? Not anything that I can think of off the top of my head. Certainly nothing recent.
What was that game I read about a few years back… I think it was kind of experimental, indie, and I think most of the gameplay is as a parent interacting with your kid who is dying of cancer. I read about it on Penny Arcade and I was really torn, both really wanting to play it, and wanting to stay as far away as possible.