What grinding? Monsters stay dead forever per act. Once a new act starts there is a respawn but almost every game does this. You can't force respawns except through advancing the story.
For those interested in trying Prey, ignore Joxer's false warning. Prey has very, very little respawn that even a girl scout could handle. I assume he got beat up by mimics and couldn't finish….
If you like System Shock 2, this is a no-brainer purchase.
I know. I'm on a baiting mission this week. Some weeks I just troll. This is one.