Likely.
I'm taking a break from it for now.
My latest game, in summary: played as the Byzantines. Took a defensive strategy: hub-and-spoke colonization, growth-oriented strategy, built the Great Wall and whole bunch of cultural stuff. Things went rather well; I was solidly in the middle of the pack for a quite a while; a few skirmishes with Shaka Zulu just to my south. Then I went on an ill-advised campaign against him: captured three cities and got him to convert to Buddhism. Then the Apostolic Palace ordered me to return one of them to him, leaving the biggest one completely isolated and indefensible. I eventually had to slink back home with most of my army intact but nothing to show for the war -- except falling behind in research. I continued until about 1770, by which time Abraham Lincoln, Hannibal, Shaka Zulu, and Moctezuma were waging a war of extermination against me. I was holding off their attacks, but it turned into a grinding war of attrition that I really had no hope of winning (due to my tech disadvantage), so I resigned.
But it was certainly my most successful campaign yet. I was doing OK at the tactical level; what lost me the game was my poor strategic decision to go after Shaka Zulu before I was strong enough to really overwhelm him, compounded by my even stupider decision to request that he convert to Buddhism, thereby subjecting myself to the whims of the apostolic palace, or risk screwing up my critical alliance with my next-door neighbor, the Ottomans, and very likely get caught in a two-front war that would quickly crush me.
Come to think of it, it's kinda amusing that, as the Byzantines, my one, true friend through the entire game was the Ottoman Empire.