Wasn't there this kind of poll already out there?
Nevertheless, Drakensang 2 (The River of Time) is THE game for me. The only old school RPG we're going to get... ever.
Though, Two Worlds 2 and new Fallout also seem interesting. Two Worlds 2 seems very good if you read the interviews and look at screenshots, it seems that they fixed lot of issues that were bothering Two Worlds 1, which was basically cheap Oblivion clone. Fallout New Vegas also seems to correct lot of issues that F3 had without mods, but I'm a bit suspicious because it's made by Obsidian, the company that haven't manage to pull any decent game out.
On the other hand, I don't really anticipate Gothic 4 or Deus Ex 3, because there hasn't been any info out there that would suggest that the games are going to be anything else than lausy console-dumbed-down simple RPGs.
Other very interesting game
Grim Dawn from makers of Titan Quest with the same engine, but that's most likely going to take a year or two to finish.
PS. Lot of sequels out there, where have the imagination gone?