Diablo 3 - Development Update @ UGO

UGO has a look at Diablo III that doesn't really offer much insight into the gameplay but summarises some of the known development decisions:

One of the earliest questions faced by Diablo III’s development team focused on the ways the series could be updated for a new generation of PC hardware.  Obviously, the possibility of giving the game a new 3D look was considered… for the space of a meeting.  The team chose to stick with the series’ standard isometric perspective (rather, isometric-style) from day one; changing that, they feared, would ultimately change the nature of the core gameplay too much.