Fallout: New Vegas - Midnight Launches, Digital Unlocks

The Bethblog has info on NA stores that will be opening at midnight for F:NV and global digital unlock times:

If you’re looking for a physical copy, Best Buy and GameStop are both opening stores early to accommodate midnight playtime. For a list of all Best Buy midnight openings, check the handy pop-up on this page. If you’re looking to hit up a GameStop when the clock strikes, call your local store to make sure they’re participating.

As for the digital realm, all copies of New Vegas purchased through stores like Steam, GameStop Digital and Direct2Drive will unlock for players in North/Central/South America at 12:01am PST/3:01am EST tomorrow morning. All other territories will see their copies unlock at 12:01 GMT on October 22nd.